Published Papers
Spectroscopic and Imaging Study of Combined W and Mo X-Pinches at 1 MA Z-Pinch Generators
IEEE TRANSACTIONS ON PLASMA SCIENCE, VOL. 34, NO. 5, OCTOBER 2006
Experiments with X -pinches made with both Mo and W wires have been performed on 1-MA pulsed power generators at Cornell University and University of Nevada, Reno. X-ray images and spectra have been studied and compared for three comparable in parameters with the SNL-Z machine, albeit in different configurations of X -pinch loads with Mo and W wires. For all X -pinches, the image size decreases with decreasing wave length and photoconducting diode (PCD) signals show multiple bursts except for one variant of the mixed Mo and W configurations. Time-gated, as well as time-integrated, images indicate the presence of radiation from energetic electrons. Previous experience with application of L-shell Mo modeling to various Z- and X -pinch experiments helped to determine plasma para-meters in the X -pinches studied here, and permitted identification of M-shell W spectral features useful for plasma parameter estimation.
Experiments with X -pinches made with both Mo and W wires have been performed on 1-MA pulsed power generators at Cornell University and University of Nevada, Reno. X-ray images and spectra have been studied and compared for three comparable in parameters with the SNL-Z machine, albeit in different configurations of X -pinch loads with Mo and W wires. For all X -pinches, the image size decreases with decreasing wave length and photoconducting diode (PCD) signals show multiple bursts except for one variant of the mixed Mo and W configurations. Time-gated, as well as time-integrated, images indicate the presence of radiation from energetic electrons. Previous experience with application of L-shell Mo modeling to various Z- and X -pinch experiments helped to determine plasma para-meters in the X -pinches studied here, and permitted identification of M-shell W spectral features useful for plasma parameter estimation.
Oral Examination
Active Transport Model of Caveolae Across Microtubules
This paper, submitted to fulfill the final requirement for Ph.D. candidacy, outlines
both the current and prospective research done under the direction of Dr. Avijit
Ghosh. In it, I seek to understand a subset of the MAPK signal transduction pathway
involving signaling from EGF. While the normal channels of endocytosis are generally
understood via clathrin-coated pits, under oxidative stress the role of caveolae play
an increasingly important role. In this paper, a model is developed to simulate active
transport of these caveolae along microtubulin from the plasma membrane into the
cytosol. A background in the numerical methods is developed to give the reader a firm
understanding of the processes involved. While the problem can be considered in an
isolated environment I will describe merging active transport into a much larger model
of the complete MAPK pathway.
Unpublished Graduate Papers
While not being having the polish of a professional journal, the papers below represent a cross-sampling of some of my better graduate work.
A proposed optimization of Genetic Algorithms
The aim of this paper is to propose an extended methodology building upon the basis
of genetic algorithms (GA). An introduction to the basic steps of function
optimization is given in the form of the method of steepest descents. The limitations
to this method and others similar to it are shown. While many algorithms exist for
linear systems, we hypothesize a general non-linear result using genetic algorithms.
GA's are then introduced in a framework that will be expanded beyond its traditional
boundaries. Instead of seeking the solution itself, we propose that new information
can be gleaned by maximizing the method of solutions to a similar
class of problems.
A novel application of Optical Tweezing for submicron motors
Optical tweezers, along with other single molecule methods, have found incredible versatility in
the study of biological systems. This paper proposes their use to create an optical rotor using
two intersecting perpendicular laser traps, and expounds on various
applications.
A brief graduate introduction to Lanczos vectors
This paper is intended as a graduate-level introduction to the theory and application of Lanczos
procedures. A theoretical introduction will be developed for exact and finite precision matrices.
The block symmetric method for real symmetric matrices will be introduced for their versatility
in dealing with large, dense matrices that are common in many real-world engineering problems.
A sample calculation is given to illustrate the Lanczos procedures in exact arithmetic. Sample
code in C++ is also provided as a starting point for interested parties.
An application of the Lanczos routine
In this paper a practical implementation of the Lanczos method is applied to a real-world
quantum mechanical system. A two dimensional banded symmetric Hamiltonian is introduced
and the first ten eigenpairs are plotted. A brief overview of the
Lanczos procedure is also given to elucidate the inner workings of the
process.