Our lab investigates protein folding mechanisms using single
molecule manipulation techniques.
Within last ten years or so, single molecule techniques have
developed into powerful tools for many branches for physical and
Since biological macromolecules are remarkably complex and
variable, single molecule studies have generated significant new
insights into the mechanisms of their functionality in cells and
These methods have significant advantages over
more static methods since they are designed to make observations on
molecules as they move in time and space.